Computational Science Technical Note CSTN-149

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Simulating Anaesthetic Effects on a Network of Spiking Neurons with Graphics Processing Units

A. Leist, C.J. Scogings and K.A. Hawick

Archived March 2011, Revised April 2012

Abstract

The structure and emergent behaviours of neuronal networks remain important unknowns but can be investigated by computer simulation of biologically plausible networks of microscopically simple individual neurons. We describe a software model developed to simulate in excess of $10^6$ individual Izhikevich neurons with connectivities of in excess of 100 connections per neuron. We simulate the effect of adjusting some of the microscopic neuronal parameters and observe emergent oscillatory phenomena that relate to the introduction of anaesthetic drugs on the collective neuronal system. We report some preliminary computational performance results and comment on the feasibility of simulating realistic sized collective networks of cortical spiking neurons.

Keywords: GPU; CUDA; spiking cortical neurons; anaesthesia

Full Document Text: PDF version.

Citation Information: BiBTeX database for CSTN Notes.

BiBTeX reference:

@INPROCEEDINGS{CSTN-149,
  author = {A. Leist and C. J. Scogings and K. A. Hawick},
  title = {Simulating Anaesthetic Effects on a Network of Spiking Neurons with
	Graphics Processing Units},
  booktitle = {Proc. International Conference on Bioinformatics and Computational
	Biology (BIOCOMP'12)},
  year = {2012},
  pages = {236-242},
  address = {Las Vegas, USA},
  month = {16-19 July},
  publisher = {CSREA},
  institution = {Computer Science, Massey University},
  timestamp = {2012.05.03}
}


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